• Colony whole genome sequencing of hematopoietic stem and progenitor cell-derived colonies from 2 dual SF3B1-mutant MDS-RS patients

This dataset consists of whole genome sequencing data from single cell-derived colonies obtained through colony-forming assays and culture of FACS-purified hematopoietic stem cells (HSC), multipotent progenitors (MPP), m...

• TARGET-seq genotyped single-cell RNA sequencing of hematopoietic stem cells and megakaryocyte-erythroid progenitor cells from a dual SF3B1-mutant MDS-RS patient and 3 healthy donors

This dataset consists of TARGETseq (genotype-targeted plate-based SmartSeq2) single-cell RNA sequencing data of purified hematopoietic stem cells (HSC) and megakaryocyte-erythroid progenitors (MEP) from the bone marrow o...

• 10X single-cell RNA sequencing of hematopoietic stem and progenitor cells from a dual SF3B1-mutant MDS-RS patient and a healthy donor

This dataset consists of 10X single-cell RNA sequencing data of bone marrow cells (CD34+ stem cells) obtained from two clinical visits of a dual SF3B1-mutant MDS-RS patient (Patient 1 in the associated publication: visit...

• Detailed description of the image analysis workflow, including machine learning model training dataset, for the article: "Phosphate starvation decouples cell differentiation from DNA replication control in the dimorphic bacterium Caulobacter crescentus", Hallgren et al. (2023; PLOS Genetics).

This dataset contains a detailed description of the image analysis procedure used in Hallgren et al. (2023; PLOS Genetics) to perform single-cell measurements of the bacterium Caulobacter crescentus. More specifically, t...

• Smart-seq3 and Smart-seq3xpress single-cell RNA sequencing of bone marrow cells from MDS-RS patients

This dataset consists of Smart-seq3 single-cell RNA sequencing data of purified RS from the bone marrow and peripheral blood of 2 MDS-RS patients; and Smart-seq3xpress single-cell RNA sequencing data of FACS-sorted hemat...

• 10X single-cell RNA sequencing of bone marrow cells from MDS-RS patients and healthy donors

This dataset consists of single-cell RNA sequencing data of bone marrow cells (CD34+ stem cells, GPA+ erythroblasts, ring sideroblasts and mononuclear cells) obtained from multiple healthy bone marrow donors and MDS-RS p...

• Bulk RNA sequencing of bone marrow cells from MDS-RS patients and healthy donors

This dataset consists of bulk RNA sequencing data of MACS-separated bone marrow cells (CD34+ stem cells, GPA+ erythroblasts, CD71+ reticulocytes, ring sideroblasts and siderocytes) obtained from multiple healthy bone mar...

• TMT proteomics of erythroblasts from healthy donors and erythroblasts/ring sideroblasts from MDS-RS patients

This dataset consists of semi-quantitative 10-plex TMT proteomics analysis of FACS-separated bone marrow cells obtained from 3 healthy bone marrow donors and 3 MDS-RS patients. The objective of this data collection was t...